Top 10 Patient Portal Software Comparison – Find the Right Solution

Choosing the right Patient Portal Software can be challenging with so many options available. To simplify your decision-making, we have created this comprehensive comparison table of the top 10 Patient Portal Software solutions. Compare their features, pricing, user ratings, and overall performance to find the perfect fit for your needs. Whether you're looking for affordability, advanced features, or seamless integrations, this side-by-side analysis will help you make an informed choice. Whether you’re a small business, enterprise, or individual user, explore this in-depth top 10 Patient Portal Software comparison to select the best solution with confidence.

Comparison Table of Top 10 Patient Portal Software

Product
Caspio

Caspio
NextGen Healthcare EHR

NextGen Healthcare EHR
SimplePractice

SimplePractice
RXNT

RXNT
My Clients Plus

My Clients Plus
TheraNest

TheraNest
Pabau

Pabau
Mend

Mend
EHR YOUR WAY

EHR YOUR WAY
BestoSys

BestoSys
Review & Ratings

No reviews available

No reviews available

No reviews available

No reviews available

No reviews available

No reviews available

No reviews available

No reviews available

No reviews available

No reviews available
Description

Caspio is a user-friendly, no-code platform empowering businesses to create... Read more about Caspio

NextGen Healthcare EHR is a robust electronic health record software... Read more about NextGen Healthcare EHR

SimplePractice is a user-friendly appointment scheduling software designed to streamline... Read more about SimplePractice

RXNT is a versatile healthcare software that integrates Electronic Health... Read more about RXNT

My Clients Plus is a specialized mental health software designed... Read more about My Clients Plus

TheraNest is an advanced electronic health records (EHR) software specifically... Read more about TheraNest

Pabau is a comprehensive clinic management software primarily designed for... Read more about Pabau

Mend is a comprehensive telemedicine software solution designed to streamline... Read more about Mend

EHR YOUR WAY is a specialized electronic health record (EHR)... Read more about EHR YOUR WAY

BestoSys is a versatile software solution tailored for dental and... Read more about BestoSys

Free Trial

14 Days

NA

Available

NA

Available

15 Days

NA

NA

NA

NA
Starting Price

$3285 Per Month

NA

$14 Per Month

$319 Per Year

$29 Per Month

$39 Per Month

$28 Per Month

$700 Per Month

NA
Features
Health Record Access
Client Portal
Appointment Scheduling
Billing & Invoicing
HIPAA Compliant
Prescription Renewal
Lab Results
Multi-Location
Document Management
Secure Messaging
Self Service Portal
Telemedicine
Medical Billing
For Medical Purposes
Artificial Intelligence
Other Info
Deployment
  • Cloud Hosted
  • Cloud Hosted
  • Cloud Hosted
  • Cloud Hosted
  • Cloud Hosted
  • Cloud Hosted
  • Cloud Hosted
  • Cloud Hosted
  • Cloud Hosted
  • Cloud Hosted
Devices Supported
  • Web-Based
  • Web-Based
  • iPhone
  • Android
  • Web-Based
  • iPhone
  • Android
  • Mac
  • Web-Based
  • iPhone
  • Android
  • Mac
  • Web-Based
  • Web-Based
  • Web-Based
  • iPhone
  • Windows
  • Mac
  • Web-Based
  • iPhone
  • Android
  • Web-Based
  • iPhone
  • Android
  • Mac
  • Web-Based
  • iPhone
  • Android
Pricing Model
  • Flat Rate
 NA
  • Flat Rate
  • Usage Based
  • Contact Vendor
  • Contact Vendor
  • Per User
  • Per Feature
  • Contact Vendor
  • Contact Vendor
Support
  • 24x7 Support
  • Email
  • Phone
  • Chat
  • Knowledge Base
  • 24x7 Support
  • Email
  • Phone
  • Chat
  • Email
  • Phone
  • Chat
  • Knowledge Base
  • FAQs/Forum
  • Email
  • Phone
  • Chat
  • Knowledge Base
  • Email
  • Phone
  • Chat
  • Knowledge Base
  • FAQs/Forum
  • Email
  • Phone
  • Chat
  • Knowledge Base
  • FAQs/Forum
  • 24x7 Support
  • Email
  • Phone
  • Chat
  • Knowledge Base
  • 24x7 Support
  • Email
  • Phone
  • Chat
  • Knowledge Base
  • FAQs/Forum
  • Email
  • Phone
  • Chat
  • Knowledge Base
  • FAQs/Forum
  • Email
  • Phone
Target Company Size
  • Self-Employed
  • Small-Business
  • Midsize-Business
  • Large-Enterprise-Business
  • Self-Employed
  • Small-Business
  • Midsize-Business
  • Large-Enterprise-Business
  • Self-Employed
  • Small-Business
  • Midsize-Business
  • Self-Employed
  • Small-Business
  • Midsize-Business
  • Large-Enterprise-Business
  • Self-Employed
  • Small-Business
  • Midsize-Business
  • Self-Employed
  • Small-Business
  • Midsize-Business
  • Self-Employed
  • Small-Business
  • Midsize-Business
  • Large-Enterprise-Business
  • Self-Employed
  • Small-Business
  • Midsize-Business
  • Self-Employed
  • Small-Business
  • Midsize-Business
  • Self-Employed
  • Small-Business
  • Midsize-Business
  • Large-Enterprise-Business

FAQs About Patient Portal Software Comparison

With so many Patient Portal Software solutions available, a side-by-side comparison helps you identify which tool offers the best features, pricing, and user experience for your specific needs. By evaluating multiple options at once, you can pinpoint the solution that aligns with your budget, technical requirements, and business goals.

Absolutely! Depending on the tool, you may discover:

  • Free Version options like Mend (basic features remain free for life)
  • Free Trial offerings such as Caspio, SimplePractice, My Clients Plus and TheraNest (test premium features before committing)

These budget-friendly Patient Portal Software solutions can be perfect for startups or small businesses, although they often come with usage caps or feature limitations. Always review each product’s details to ensure it meets your specific needs.

Small businesses often benefit from budget-friendly, easy-to-deploy, and intuitive platforms. For example, Caspio, NextGen Healthcare EHR, SimplePractice, RXNT, My Clients Plus, TheraNest, Pabau, Mend, EHR YOUR WAY and BestoSys are popular picks in the Patient Portal Software category, offering simple setup, affordable plans, and essential features suitable for smaller teams.

Enterprises typically require advanced security, robust reporting, and scalability. Tools like Caspio, NextGen Healthcare EHR, RXNT, Pabau and BestoSys in the Patient Portal Software category excel at handling complex workflows, large user bases, and offer dedicated enterprise support.

Yes! Many Patient Portal Software solutions—such as NextGen Healthcare EHR, SimplePractice, RXNT, Pabau, Mend, EHR YOUR WAY and BestoSys—provide mobile apps for on-the-go access. This allows you to manage features, collaborate in real time, and stay updated wherever you are. If mobile functionality is crucial for your business, be sure to confirm each software’s app availability and compatibility.